exRNAdisease

Entry Detail

General Information

Database ID:

exR0198037

RNA Name:

hsa-miR-628-5p

RNA Type:

miRNA

Chromosome:

chr15

Starnd:

-

Coordinate:

Start Site(bp):

55372991

End Site(bp):

55373012

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AGTRAP	chr1	11736084	11754802	+
ASF1B	chr19	14119512	14136613	-
CA12	chr15	63321378	63381846	-
CORO2B	chr15	68578993	68727806	+
MEIS2	chr15	36889204	37101299	-
RAB31	chr18	9708275	9862551	+
RACGAP1	chr12	49976923	50033136	-
ZBTB39	chr12	56998836	57006546	-
ZSCAN22	chr19	58326994	58342332	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001550	chr5	167915606	167921655	+
hsa_circ_0000540	chr14	55799534	55821940	+
hsa_circ_0000642	chr15	80390757	80415142	+
hsa_circ_0001492	chr5	65284462	65290692	+
hsa_circ_0000643	chr15	80412669	80415142	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC020978.7	chr16	68224713	68227734	+
KCNQ1OT1	chr11	2608328	2699994	-
NEAT1	chr11	65422774	65445540	+

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia