exRNAdisease

Entry Detail

General Information

Database ID:

exR0198051

RNA Name:

hsa-miR-641

RNA Type:

miRNA

Chromosome:

chr19

Starnd:

-

Coordinate:

Start Site(bp):

40282603

End Site(bp):

40282626

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AIF1L	chr9	131096476	131123152	+
AKT2	chr19	40230317	40285536	-
C19orf47	chr19	40319536	40348527	-
CDKN1A	chr6	36676460	36687339	+
F11R	chr1	160995211	161021343	-
FOXN3	chr14	89124871	89619149	-
GATAD2B	chr1	153789030	153923360	-
GCNT2	chr6	10492223	10629368	+
GNPTAB	chr12	101745499	101830959	-
HMGA2	chr12	65824131	65966295	+
ICE1	chr5	5420664	5490220	+
JPT1	chr17	75135248	75168281	-
LSM14A	chr19	34172504	34229515	+
MED13L	chr12	115953872	116277719	-
PRSS16	chr6	27247701	27256624	+
SETD7	chr4	139495941	139606699	-
SOCS3	chr17	78356778	78360077	-
SYNJ2BP	chr14	70366499	70417090	-
SYNJ2BP-COX16	chr14	70326064	70417074	-
ZDHHC6	chr10	112424428	112446917	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001085	chr2	191765289	191789319	+
hsa_circ_0001168	chr20	47691321	47707559	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC125257.1	chr17	41848518	41851447	-
AC239868.1	chr1	149861271	149862504	+
AL034397.3	chrX	66015461	66020422	+
AL049795.2	chr1	32170733	32176568	+
AL355075.4	chr14	20343048	20343685	-
DLEU2	chr13	49956670	50125720	-
LINC00641	chr14	21200079	21206900	-
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
OIP5-AS1	chr15	41283990	41309737	+
SNHG1	chr11	62851984	62855953	-
SNHG16	chr17	76557764	76565348	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia