exRNAdisease

Entry Detail

General Information

Database ID:

exR0198065

RNA Name:

hsa-miR-650

RNA Type:

miRNA

Chromosome:

chr22

Starnd:

+

Coordinate:

Start Site(bp):

22822791

End Site(bp):

22822811

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
POM121C	chr7	75416786	75486299	-
ATXN2L	chr16	28823035	28837237	+
RNF220	chr1	44405194	44651724	+
POLE3	chr9	113407235	113410675	-
SFN	chr1	26863149	26864456	+
SH3GL1	chr19	4360370	4400547	-
STOM	chr9	121338987	121370304	-
HNRNPUL1	chr19	41262496	41307787	+
LMNA	chr1	156082573	156140089	+
SLC9A3R1	chr17	74748628	74769353	+
HPCAL1	chr2	10302889	10427617	+
TRAF7	chr16	2155698	2178129	+
GBF1	chr10	102245532	102382899	+
ZNF623	chr8	143636013	143656418	+
USP22	chr17	20999596	21043760	-
POLDIP3	chr22	42583721	42614962	-
VHL	chr3	10141008	10152220	+
ABL1	chr9	130713016	130887675	+
TSKU	chr11	76782251	76798153	+
TRAPPC10	chr21	44012309	44106552	+
SLC29A1	chr6	44219553	44234142	+
HIF1AN	chr10	100529072	100559998	+
NBL1	chr1	19596979	19658456	+
AFAP1	chr4	7758714	7939926	-
CBFA2T3	chr16	88874858	88977207	-
AKT2	chr19	40230317	40285536	-
RAB1B	chr11	66268590	66277492	+
PAK4	chr19	39125770	39182816	+
DUSP8	chr11	1554051	1572271	-
TESMIN	chr11	68707440	68751520	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001168	chr20	47691321	47707559	+
hsa_circ_0001146	chr20	34241449	34246936	-

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC068768.1	chr12	123262060	123262402	+
AC118758.3	chr7	56809214	56848800	-
AL049796.1	chr1	93847174	93848939	+
AL355075.4	chr14	20343048	20343685	-
DSCAM-AS1	chr21	40383083	40385358	+
KCNQ1OT1	chr11	2608328	2699994	-
LINC01772	chr1	16460948	16468481	+
MIR155HG	chr21	25561909	25575168	+
MIR663AHG	chr20	26167817	26251546	-
NEAT1	chr11	65422774	65445540	+
TUG1	chr22	30969245	30979395	+

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia