exRNAdisease

Entry Detail

General Information

Database ID:

exR0198108

RNA Name:

hsa-miR-654-3p

RNA Type:

miRNA

Chromosome:

chr14

Starnd:

+

Coordinate:

Start Site(bp):

101040269

End Site(bp):

101040290

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ANKRD49	chr11	94493979	94499578	+
ATAD1	chr10	87751512	87841343	-
CAMTA1	chr1	6785454	7769706	+
CLN8	chr8	1755778	1801711	+
EPB41L1	chr20	36091504	36232799	+
RAB10	chr2	26034084	26137454	+
RNF220	chr1	44405194	44651724	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001146	chr20	34241449	34246936	-

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC005899.4	chr17	32328441	32329395	+
AC079781.5	chr7	97851688	97972985	-
AL049795.2	chr1	32170733	32176568	+
AL358472.3	chr1	153966516	153966930	+
HCG11	chr6	26521709	26527404	+
MCM3AP-AS1	chr21	46229196	46259390	+
NEAT1	chr11	65422774	65445540	+
SNHG1	chr11	62851984	62855953	-
THUMPD3-AS1	chr3	9349689	9398579	-
TUG1	chr22	30969245	30979395	+
XIST	chrX	73820649	73852723	-
ZFAS1	chr20	49278178	49299600	+

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia