exRNAdisease

Entry Detail

General Information

Database ID:

exR0198109

RNA Name:

hsa-miR-654-5p

RNA Type:

miRNA

Chromosome:

chr14

Starnd:

+

Coordinate:

Start Site(bp):

101040234

End Site(bp):

101040255

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
BCL9L	chr11	118893875	118925608	-
ATP11A	chr13	112690329	112887168	+
PHB	chr17	49404049	49414905	-
ZDHHC3	chr3	44915257	44976185	-
PKM	chr15	72199029	72231822	-
ATXN7L3	chr17	44191805	44200113	-
SH3PXD2A	chr10	103594027	103855543	-
ITGA5	chr12	54395261	54419266	-
TP53	chr17	7661779	7687550	-
CBFA2T3	chr16	88874858	88977207	-
CS	chr12	56271699	56300391	-
LY6E	chr8	143017982	143023832	+
SPINT1	chr15	40844018	40858207	+
AGTRAP	chr1	11736084	11754802	+
URM1	chr9	128371361	128392016	+
BCL7A	chr12	122019422	122062044	+
MEF2D	chr1	156463727	156500779	-
DHCR24	chr1	54849627	54887195	-
JADE2	chr5	134524312	134583230	+
LSM12	chr17	44034328	44067619	-
ZMIZ1	chr10	79068966	79316528	+
TOB2	chr22	41433494	41446801	-
ACTN4	chr19	38647649	38731589	+
XPO6	chr16	28097979	28211920	-
KMT2D	chr12	49018975	49059774	-
SMAD3	chr15	67063763	67195169	+
BCAM	chr19	44809071	44821421	+
IGF2BP1	chr17	48997385	49056145	+
GID4	chr17	18039408	18068405	+
NID1	chr1	235975830	236065109	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000417	chr12	69644908	69656342	+
hsa_circ_0000642	chr15	80390757	80415142	+
hsa_circ_0000816	chr17	80521229	80526077	+
hsa_circ_0000643	chr15	80412669	80415142	+
hsa_circ_0000943	chr19	47421744	47440665	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC239868.1	chr1	149861271	149862504	+
AL035458.2	chr20	34234840	34281173	-
AL356488.2	chr1	109100193	109100619	+
NEAT1	chr11	65422774	65445540	+
NORAD	chr20	36045618	36051018	-
OIP5-AS1	chr15	41283990	41309737	+
STAG3L5P-PVRIG2P-PILRB	chr7	100336104	100367831	+
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia