exRNAdisease

Entry Detail

General Information

Database ID:

exR0198563

RNA Name:

hsa-miR-7705

RNA Type:

miRNA

Chromosome:

chr8

Starnd:

-

Coordinate:

Start Site(bp):

100703002

End Site(bp):

100703024

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
CTNND1	chr11	57753243	57819546	+
FSTL1	chr3	120392293	120450993	-
CTNNA1	chr5	138610967	138935034	+
EIF3H	chr8	116642130	116766925	-
MLF1	chr3	158571163	158607252	+
NTPCR	chr1	232950605	232983882	+
PABPC1	chr8	100685816	100722809	-
PABPC3	chr13	25095868	25099254	+
RPL27	chr17	42998273	43002959	+
RPLP2	chr11	809965	812880	+
RPP30	chr10	90871716	90908553	+
RPS6	chr9	19375715	19380236	-
SRSF1	chr17	58000919	58007346	-
TTYH2	chr17	74213571	74262020	+

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

NA

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia