exRNAdisease

Entry Detail

General Information

Database ID:

exR0198627

RNA Name:

hsa-miR-873-5p

RNA Type:

miRNA

Chromosome:

chr9

Starnd:

-

Coordinate:

Start Site(bp):

28888925

End Site(bp):

28888945

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
CACUL1	chr10	118674167	118755249	-
ICAM1	chr19	10271093	10286615	+
IDS	chrX	149476988	149521096	-
NUDT3	chr6	34279679	34392669	-
EPHA4	chr2	221418027	221574202	-
TRIOBP	chr22	37697048	37776556	+
BCL2L11	chr2	111119378	111168445	+
SEPHS2	chr16	30443631	30445874	-
PFKFB3	chr10	6144934	6254644	+
PSD3	chr8	18527303	19084730	-
PRDM15	chr21	41798225	41879482	-
DLG3	chrX	70444835	70505490	+
ORAI1	chr12	121626550	121642677	+
LMBR1	chr7	156668946	156893216	-
TRIO	chr5	14143342	14532128	+
OTUB1	chr11	63985853	64001811	+
HDGF	chr1	156742109	156766925	-
FAM222B	chr17	28755978	28855232	-
TBX3	chr12	114670255	114684175	-
BCL9L	chr11	118893875	118925608	-
CTTNBP2NL	chr1	112396214	112463456	+
CENPX	chr17	82018702	82024107	-
SMG5	chr1	156249224	156282825	-
PLAGL2	chr20	32192504	32207743	-
BICRA	chr19	47608196	47703277	+
CSNK1E	chr22	38290691	38318084	-
TMEM179B	chr11	62787402	62790400	+
DBNDD1	chr16	90004871	90020128	-
ZXDB	chrX	57591652	57597545	+
APPL2	chr12	105173297	105236203	-

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000417	chr12	69644908	69656342	+
hsa_circ_0000987	chr2	30748452	30756180	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC002116.1	chr19	36008638	36014235	-
AC079781.5	chr7	97851688	97972985	-
AC084809.2	chr17	32905662	32906584	+
AC239868.1	chr1	149861271	149862504	+
AC245033.4	chr15	82533175	82540008	-
AL022311.1	chr22	37876148	37895563	+
AL049543.1	chr6	28587378	28591747	+
AL355987.2	chr9	136800366	136829466	+
GAS5	chr1	173858559	173868882	-
LINC01535	chr19	37251885	37265535	+
MALAT1	chr11	65497688	65506516	+
MIR4435-2HG	chr2	111006015	111523376	-
MIR503HG	chrX	134543119	134546642	-
NEAT1	chr11	65422774	65445540	+
SNHG15	chr7	44983023	44986961	-
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia