exRNAdisease

Entry Detail

General Information

Database ID:

exR0198660

RNA Name:

hsa-miR-92a-3p

RNA Type:

miRNA

Chromosome:

chrX

Starnd:

-

Coordinate:

Start Site(bp):

134169544

End Site(bp):

134169565

External Links:

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE120584
Description:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:	Disease vs Control
Case Disease Type:	Alzheimer's Disease
Case Disease SubType:	NA
Case Sample:	Alzheimer's Disease
Control Sample:	Normal
Number of Case:	1021
Number of Control:	288
Number of Samples:	1309

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
MAZ	chr16	29806106	29811164	+
RPS8	chr1	44775251	44778779	+
ESRP1	chr8	94641074	94707466	+
PTPRZ1	chr7	121873089	122062036	+
YIPF3	chr6	43511832	43516985	-
SEC63	chr6	107867756	107958208	-
NPM1	chr5	171387116	171411137	+
USP21	chr1	161159450	161165723	+
ZNF330	chr4	141220887	141234697	+
HBE1	chr11	5268345	5505652	-
EHMT2	chr6	31879759	31897687	-
PITPNA	chr17	1517718	1562792	-
RBBP5	chr1	205086142	205122015	-
PNKD	chr2	218270392	218346793	+
SMC1A	chrX	53374149	53422728	-
RWDD1	chr6	116571409	116597675	+
GLCE	chr15	69160584	69272217	+
CEP89	chr19	32875925	32971991	-
PPP3CB	chr10	73436428	73496024	-
HMGB1	chr13	30456704	30617597	-
KLF4	chr9	107484852	107490482	-
MRPS16	chr10	73248843	73252693	-
TCP1	chr6	159778498	159789703	-
EZR	chr6	158765741	158819368	-
PSMB8	chr6	32840717	32844679	-
RPL17-C18orf32	chr18	49481681	49492479	-
OGFOD1	chr16	56451521	56479104	+
MCM3	chr6	52264014	52284881	-
EIF4G2	chr11	10797050	10808940	-
RPL13A	chr19	49487554	49492308	+

miRNA targets:

NA

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0001005	chr2	53921020	53978078	-
hsa_circ_0001414	chr4	56277780	56284152	+
hsa_circ_0000126	chr1	150997086	150999803	+

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC005394.2	chr19	28435388	28727680	-
AC074117.1	chr2	27356246	27367622	+
AC130650.2	chr16	14150833	14153235	+
DAPK1-IT1	chr9	87553454	87554459	+
LINC01128	chr1	825138	859446	+
MALAT1	chr11	65497688	65506516	+
NORAD	chr20	36045618	36051018	-
OIP5-AS1	chr15	41283990	41309737	+
PITPNA-AS1	chr17	1516931	1518096	+
PURPL	chr5	27217714	27496994	+
SNHG5	chr6	85650491	85678932	-
XIST	chrX	73820649	73852723	-

Display:

Experiment Detail

GEO ID:	GSE120584
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21263
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2532
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:	miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID:	30820472
Title:	Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:	Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:	Commun Biol. 2019 Feb 25;2:77.
Description:	we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia