exRNAdisease

Entry Detail

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General Information

Database ID: exR0201102 RNA Name: hsa-miR-7847-3p RNA Type: miRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 1880105 End Site(bp): 1880125 External Links: hsa-miR-7847-3p

Disease Information

Disease Name: Dementia with Lewy Bodies Disease Category: Nervous System Diseases MeSH ID: D020961 Type: Diseases Category/Nervous System Diseases Alias: Lewy Body Disease//Diffuse Lewy Body Disease//Lewy Body Dementia//Cortical Lewy Body Disease//Lewy Body Disease, Cortical//Lewy Body Type Senile Dementia//Lewy Body Disease, Diffuse//Dementia, Lewy Body

Expression Detail

GEO ID: GSE120584 Description: Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data Experimental Design: Disease vs Control Case Disease Type: Alzheimer's Disease Case Disease SubType: NA Case Sample: Dementia with Lewy Bodies Control Sample: Normal Number of Case: 1021 Number of Control: 288 Number of Samples: 1309

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MAVS chr20 3846799 3876123 + ACTB chr7 5527148 5563784 - CRELD1 chr3 9933816 9945406 + EVC chr4 5711201 5814305 + HNRNPUL2 chr11 62712630 62727457 - HPRT1 chrX 134460165 134520513 + MRPL35 chr2 86199355 86213790 + MYC chr8 127735434 127742951 + PEX19 chr1 160276812 160286348 - RPL10 chrX 154389955 154409168 + RPS15 chr19 1438358 1440494 + SLC25A6 chrX 1386152 1392113 - SRRM2 chr16 2752626 2772538 + TMSB4X chrX 12975110 12977227 + WIPF1 chr2 174559572 174682916 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE120584 Sample Source: Blood Source Fraction: Serum Platform: GPL21263 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2532 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.). RNA library preparation protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID: 30820472 Title: Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data Author: Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S Journal: Commun Biol. 2019 Feb 25;2:77. Description: we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia