Entry Detail


General Information

Database ID:exR0201805
RNA Name:hsa-miR-3163
RNA Type:miRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):66934476End Site(bp):66934497
External Links:hsa-miR-3163



Disease Information

Disease Name:Mild Cognitive Impairment
Disease Category:Other Diseases
MeSH ID:D060825
Type:Psychiatry and Psychology Category/Mental Disorders
Alias:Cognitive Dysfunction//Cognitive Dysfunctions//Dysfunction, Cognitive//Dysfunctions, Cognitive//Cognitive Impairments//Cognitive Impairment//Impairment, Cognitive//Impairments, Cognitive//Mild Cognitive Impairment//Cognitive Impairment, Mild//Cognitive Impairments, Mild//Impairment, Mild Cognitive//Impairments, Mild Cognitive//Mild Cognitive Impairments//Mild Neurocognitive Disorder//Disorder, Mild Neurocognitive//Disorders, Mild Neurocognitive//Mild Neurocognitive Disorders//Neurocognitive Disorder, Mild//Neurocognitive Disorders, Mild//Cognitive Decline//Cognitive Declines//Decline, Cognitive//Declines, Cognitive//Mental Deterioration//Deterioration, Mental//Deteriorations, Mental//Mental Deteriorations



Expression Detail

GEO ID:GSE120584
Description:Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Experimental Design:Disease vs Control
Case Disease Type:Alzheimer's Disease
Case Disease SubType:NA
Case Sample:Mild Cognitive Impairment
Control Sample:Normal
Number of Case:1021
Number of Control:288
Number of Samples:1309





Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000642
chr15
80390757
80415142
+
hsa_circ_0000643
chr15
80412669
80415142
+
hsa_circ_0001414
chr4
56277780
56284152
+
hsa_circ_0000106
chr1
111690263
111703918
+
hsa_circ_0000552
chr14
71880664
71948928
+
hsa_circ_0000799
chr17
65941524
65972074
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007038.1
chr2
210028417
210029156
+
AC010980.2
chr2
222317242
222318653
-
AC021078.1
chr5
149494314
149504670
-
AC022167.2
chr16
8848105
8860456
+
AC051619.7
chr15
45200325
45200632
-
AC092718.4
chr16
81030770
81031485
+
AC243964.3
chr19
44631573
44725217
-
DLEU2
chr13
49956670
50125720
-
DSCAM-AS1
chr21
40383083
40385358
+
FGD5-AS1
chr3
14920347
14948424
-
GABPB1-AS1
chr15
50354959
50372202
+
HCG11
chr6
26521709
26527404
+
LINC00662
chr19
27681072
27794005
-
MALAT1
chr11
65497688
65506516
+
MEG8
chr14
100894770
101038859
+
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
SNHG1
chr11
62851984
62855953
-
SNHG5
chr6
85650491
85678932
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE120584
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2532
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30820472
Title:Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data
Author:Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S
Journal:Commun Biol. 2019 Feb 25;2:77.
Description:we investigated potential miRNA biomarkers and constructed risk prediction models, based on a supervised principal component analysis (PCA) logistic regression method, according to the subtype of dementia