Entry Detail


General Information

Database ID:exR0231605
RNA Name:hsa-miR-1193
RNA Type:miRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):101030061End Site(bp):101030083
External Links:hsa-miR-1193



Disease Information

Disease Name:Benign bone and soft tissue tumor
Disease Category:Other Diseases
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE124158
Description:A serum miRNA classifier diagnoses bone and soft tissue sarcomas across various histological subtypes
Experimental Design:Cancer vs Control
Case Disease Type:Benign bone and soft tissue tumor
Case Disease SubType:NA
Case Sample:Benign bone and soft tissue tumor
Control Sample:Healthy
Number of Case:339
Number of Control:275
Number of Samples:614





Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC023509.1
chr12
53441741
53467528
+
AF254983.1
chr21
10482738
10605716
+
AL022311.1
chr22
37876148
37895563
+
AP000233.2
chr21
25095022
25103670
+
SNHG5
chr6
85650491
85678932
-
Display:



Experiment Detail

GEO ID:GSE124158
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30898996
Title:A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes
Author:Asano N, Matsuzaki J, Ichikawa M, Kawauchi J, Takizawa S, Aoki Y, Sakamoto H, Yoshida A, Kobayashi E, Tanzawa Y, Nakayama R, Morioka H, Matsumoto M, Nakamura M, Kondo T, Kato K, Tsuchiya N, Kawai A, Ochiya T
Journal:Nat Commun. 2019 Mar 21;10(1):1299.
Description:we investigated serum miRNA profiles from 1002 patientswith bone and soft tissue tumors representing more than 43 histological subtypes,including sarcomas, intermediate tumors, and benign tumors, to determine whether serum miRNA profiles could be used to specifically detect sarcomas.