exRNAdisease

Entry Detail

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General Information

Database ID: exR0231737 RNA Name: hsa-miR-1301-3p RNA Type: miRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 25328651 End Site(bp): 25328674 External Links: hsa-miR-1301-3p

Disease Information

Disease Name: Benign bone and soft tissue tumor Disease Category: Other Diseases MeSH ID: Type: Alias:

Expression Detail

GEO ID: GSE124158 Description: A serum miRNA classifier diagnoses bone and soft tissue sarcomas across various histological subtypes Experimental Design: Cancer vs Control Case Disease Type: Benign bone and soft tissue tumor Case Disease SubType: NA Case Sample: Benign bone and soft tissue tumor Control Sample: Healthy Number of Case: 339 Number of Control: 275 Number of Samples: 614

Regulatory Relationship

mRNA targets: NA miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001225 chr22 36684772 36684943 - hsa_circ_0001880 chr9 110084263 110087285 + hsa_circ_0000799 chr17 65941524 65972074 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC015871.3 chr15 79920195 79922455 - AC018521.1 chr17 47945424 47981736 + AC025171.4 chr5 43061395 43062441 + AC067930.1 chr8 143579636 143580670 + AC245033.4 chr15 82533175 82540008 - DANCR chr4 52712404 52720351 + JPX chrX 73944182 74070408 + KCNQ1OT1 chr11 2608328 2699994 - LINC00894 chrX 149938613 150224580 + MUC20-OT1 chr3 195658062 195739964 + NEAT1 chr11 65422774 65445540 + NNT-AS1 chr5 43571594 43603230 - PVT1 chr8 127794526 128187101 + SNHG12 chr1 28578538 28583132 - SNHG16 chr17 76557764 76565348 + Display:

Experiment Detail

GEO ID: GSE124158 Sample Source: Blood Source Fraction: Serum Platform: GPL21263 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2512 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.). RNA library preparation protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID: 30898996 Title: A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes Author: Asano N, Matsuzaki J, Ichikawa M, Kawauchi J, Takizawa S, Aoki Y, Sakamoto H, Yoshida A, Kobayashi E, Tanzawa Y, Nakayama R, Morioka H, Matsumoto M, Nakamura M, Kondo T, Kato K, Tsuchiya N, Kawai A, Ochiya T Journal: Nat Commun. 2019 Mar 21;10(1):1299. Description: we investigated serum miRNA profiles from 1002 patientswith bone and soft tissue tumors representing more than 43 histological subtypes,including sarcomas, intermediate tumors, and benign tumors, to determine whether serum miRNA profiles could be used to specifically detect sarcomas.