Entry Detail


General Information

Database ID:exR0233533
RNA Name:hsa-miR-6728-3p
RNA Type:miRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):8866502End Site(bp):8866522
External Links:hsa-miR-6728-3p



Disease Information

Disease Name:Benign bone and soft tissue tumor
Disease Category:Other Diseases
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE124158
Description:A serum miRNA classifier diagnoses bone and soft tissue sarcomas across various histological subtypes
Experimental Design:Cancer vs Control
Case Disease Type:Benign bone and soft tissue tumor
Case Disease SubType:NA
Case Sample:Benign bone and soft tissue tumor
Control Sample:Healthy
Number of Case:339
Number of Control:275
Number of Samples:614





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
EDARADD
chr1
236348257
236502915
+
ENO1
chr1
8861000
8879190
-
ENO3
chr17
4948092
4957131
+
MT-ND4
chrMT
10760
12137
+
RPS3
chr11
75399515
75422280
+
SET
chr9
128683424
128696400
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:GSE124158
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21263
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:30898996
Title:A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes
Author:Asano N, Matsuzaki J, Ichikawa M, Kawauchi J, Takizawa S, Aoki Y, Sakamoto H, Yoshida A, Kobayashi E, Tanzawa Y, Nakayama R, Morioka H, Matsumoto M, Nakamura M, Kondo T, Kato K, Tsuchiya N, Kawai A, Ochiya T
Journal:Nat Commun. 2019 Mar 21;10(1):1299.
Description:we investigated serum miRNA profiles from 1002 patientswith bone and soft tissue tumors representing more than 43 histological subtypes,including sarcomas, intermediate tumors, and benign tumors, to determine whether serum miRNA profiles could be used to specifically detect sarcomas.