exRNAdisease

General Information

Database ID:

exR0261483

RNA Name:

hsa-let-7e-5p

RNA Type:

miRNA

Chromosome:

chr19

Starnd:

Coordinate:

Start Site(bp):

51692793

End Site(bp):

51692814

External Links:

Disease Information

Disease Name:	Prostate Cancer
Disease Category:	Cancers
MeSH ID:	D011471
Type:	Neoplasms/Digestive System Neoplasms
Alias:	Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID:	GSE134266
Description:	Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray)
Experimental Design:	Cancer vs Control
Case Disease Type:	Prostate Cancer
Case Disease SubType:	Bone Metastatic Prostate Cancer
Case Sample:	Bone Metastatic Prostate Cancer
Control Sample:	Benign Prostatic Hyperplasia
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ARHGAP28	chr18	6729718	6915716	+
BACH1	chr21	29194071	29630751	+
BCAM	chr19	44809071	44821421	+
BLOC1S6	chr15	45587214	45615945	+
C15orf41	chr15	36579626	36810248	+
C19orf53	chr19	13774456	13778773	+
COIL	chr17	56938199	56961050	-
CTPS2	chrX	16587999	16712936	-
GRPEL2	chr5	149345430	149354583	+
HDLBP	chr2	241227264	241317061	-
HMGA1	chr6	34236873	34246231	+
IGDCC3	chr15	65327127	65378002	-
IGF2BP1	chr17	48997385	49056145	+
MNT	chr17	2384073	2401104	-
MPDZ	chr9	13105704	13279590	-
OPA3	chr19	45527427	45602212	-
PACS1	chr11	66070272	66244744	+
PDPR	chr16	70113626	70162537	+
PHC3	chr3	170086732	170181749	-
PLD3	chr19	40348456	40380439	+
PLPP6	chr9	4662294	4665258	+
PPARA	chr22	46150521	46243756	+
RAB40C	chr16	589357	629272	+
RANBP2	chr2	108719482	108785809	+
SH3PXD2B	chr5	172325000	172454525	-
TECPR2	chr14	102362941	102502477	+
TNRC6B	chr22	40044817	40335808	+
TRIM65	chr17	75880335	75896951	-
UBE2G2	chr21	44768580	44801826	-
YOD1	chr1	207043849	207052980	-

miRNA targets:

circRNA targets:

circRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa_circ_0000247	chr10	74474868	74475660	+
hsa_circ_0000987	chr2	30748452	30756180	+
hsa_circ_0000246	chr10	74468040	74475660	+
hsa_circ_0000018	chr1	15860731	15863309	+
hsa_circ_0000038	chr1	28800065	28802803	+
hsa_circ_0000799	chr17	65941524	65972074	+
hsa_circ_0001164	chr20	45891031	45923523	-

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC006064.5	chr12	6510275	6510522	+
AC074117.1	chr2	27356246	27367622	+
AC109460.3	chr16	28974804	28990775	+
AC124045.1	chr3	44667412	44669364	+
AP000766.1	chr11	107312132	107316271	-
ARHGAP27P1-BPTFP1-KPNA2P3	chr17	64749663	64781707	-
KCNQ1OT1	chr11	2608328	2699994	-
LINC00265	chr7	39733430	39793092	+
LINC02381	chr12	54126082	54147485	+
MIRLET7BHG	chr22	46053869	46113928	+
NEAT1	chr11	65422774	65445540	+
NUTM2A-AS1	chr10	87201647	87342612	-
SNHG16	chr17	76557764	76565348	+
SNHG4	chr5	139274102	139284899	+
TMPO-AS1	chr12	98512973	98516422	-
XIST	chrX	73820649	73852723	-
ZNF436-AS1	chr1	23368997	23371839	+

Display:

Experiment Detail

GEO ID:	GSE134266
Sample Source:	Blood
Source Fraction:	Extracellular Vesicle
Platform:	GPL25134
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	2519
Sample treatment protocol:	The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific).
RNA Extract protocol:	Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially.
RNA library preparation protocol:	Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference