exRNAdisease

Entry Detail

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General Information

Database ID: exR0261515 RNA Name: hsa-miR-1181 RNA Type: miRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 10403505 End Site(bp): 10403525 External Links: hsa-miR-1181

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CDC37 chr19 10391133 10420121 - CHD7 chr8 60678740 60868028 + IRS2 chr13 109752695 109786583 - MAZ chr16 29806106 29811164 + PIM1 chr6 37170152 37175428 + RRP1B chr21 43659560 43696079 + ZMIZ1 chr10 79068966 79316528 + CAMK4 chr5 111223653 111494886 + ELF1 chr13 40931924 41061440 - GNAS chr20 58839718 58911192 + GSPT1 chr16 11868128 11916082 - HNRNPA0 chr5 137745651 137754363 - HNRNPUL2 chr11 62712630 62727457 - HNRNPUL2-BSCL2 chr11 62690275 62727384 - IMMT chr2 86143932 86195770 - MDFIC chr7 114922154 115019202 + PRKAA2 chr1 56645314 56715335 + RAB21 chr12 71754863 71800286 + RALY chr20 33993646 34108308 + SLC4A4 chr4 71062667 71572087 + SOX1 chr13 112067149 112071706 + SPINT2 chr19 38244035 38292615 + TMEFF1 chr9 100473149 100577636 + TTC3 chr21 37073226 37203112 + U2AF1 chr21 43092956 43107587 - U2AF1L5 chr21 6484623 6499261 - UBE2D2 chr5 139526431 139628434 + ZNF282 chr7 149195546 149226238 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007216.1 chr16 11976851 11977850 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA