exRNAdisease

Entry Detail

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General Information

Database ID: exR0261570 RNA Name: hsa-miR-1248 RNA Type: miRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 186786675 End Site(bp): 186786701 External Links: hsa-miR-1248

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CHD9 chr16 53055033 53329150 + ADAM10 chr15 58588809 58749791 - COA1 chr7 43608456 43729717 - COMT chr22 19941733 19969975 + COPB1 chr11 14443440 14500027 - EIF3L chr22 37848868 37889407 + EIF4A2 chr3 186783205 186789897 + GSPT1 chr16 11868128 11916082 - HNRNPA0 chr5 137745651 137754363 - INO80B chr2 74455087 74457944 + INO80B-WBP1 chr2 74455088 74460884 + KCTD10 chr12 109448655 109477359 - MRPL13 chr8 120380761 120445402 - RPS25 chr11 119015712 119018691 - SEC24B chr4 109433772 109540896 + SERINC5 chr5 80111651 80256048 - TM9SF2 chr13 99446311 99564048 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand SNHG1 chr11 62851984 62855953 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA