exRNAdisease

Entry Detail

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General Information

Database ID: exR0261888 RNA Name: hsa-miR-221-3p RNA Type: miRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 45746180 End Site(bp): 45746202 External Links: hsa-miR-221-3p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACVR2B chr3 38453890 38493142 + AP3M1 chr10 74120255 74151063 - DNAJC14 chr12 55820960 55830824 - EFNA1 chr1 155127876 155134899 + KDSR chr18 63327726 63367228 - MPZL1 chr1 167721192 167791919 + PPIL1 chr6 36854827 36874803 - TBL1X chrX 9463295 9741037 + TUB chr11 8019244 8106112 + ZBTB5 chr9 37438102 37465450 - DDIT4 chr10 72273924 72276036 + FUS chr16 31180110 31194871 + MAPRE1 chr20 32819954 32850405 + RIPOR2 chr6 24804282 25042170 - SP4 chr7 21428043 21514822 + TUBA1B chr12 49127782 49131397 - ZNF649 chr19 51889235 51905040 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001247 chr22 46125304 46136418 + hsa_circ_0000670 chr16 9199043 9199243 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020978.7 chr16 68224713 68227734 + AC022150.4 chr19 52650437 52653284 - ARHGAP27P1-BPTFP1-KPNA2P3 chr17 64749663 64781707 - GAS5 chr1 173858559 173868882 - NEAT1 chr11 65422774 65445540 + TUG1 chr22 30969245 30979395 + TYMSOS chr18 630886 658340 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA