exRNAdisease

Entry Detail

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General Information

Database ID: exR0261911 RNA Name: hsa-miR-24-3p RNA Type: miRNA Chromosome: chr9 Starnd: + Coordinate: Start Site(bp): 95086064 End Site(bp): 95086085 External Links: hsa-miR-24-3p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AEN chr15 88621337 88632281 + AMOTL2 chr3 134355874 134375479 - APPL2 chr12 105173297 105236203 - ARPP19 chr15 52547045 52569883 - CD74 chr5 150400041 150412929 - CEP170B chr14 104865268 104896770 + CGN chr1 151510510 151538692 + CPA4 chr7 130293134 130324180 + CREG1 chr1 167529117 167553805 - CYB5B chr16 69424619 69466264 + DNAJB6 chr7 157335381 157417439 + GALNT10 chr5 154190730 154420984 + GIGYF1 chr7 100679507 100694037 - PLEKHM1 chr17 45435900 45490749 - RUBCN chr3 197668867 197749727 - STK4 chr20 44966479 45080021 + TMEM9 chr1 201134772 201171574 - WDR36 chr5 111091716 111130502 + GSK3B chr3 119821323 120094417 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000402 chr12 53670403 53671011 + hsa_circ_0000155 chr1 168007608 168014465 + hsa_circ_0000733 chr17 1561546 1562030 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand A1BG-AS1 chr19 58347718 58355455 + AC005034.3 chr2 75697583 75697996 + AC005394.2 chr19 28435388 28727680 - AC027031.2 chr8 106270144 106272902 + AC079781.5 chr7 97851688 97972985 - AC091564.7 chr11 6610883 6616594 - AL031282.2 chr1 1702736 1737688 - DIO3OS chr14 101552221 101560431 - EBLN3P chr9 37079645 37090928 + KCNQ1OT1 chr11 2608328 2699994 - MCM3AP-AS1 chr21 46229196 46259390 + MIR22HG chr17 1711493 1717174 - MIR497HG chr17 7015818 7019659 - NEAT1 chr11 65422774 65445540 + Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA