exRNAdisease

Entry Detail

---



General Information

Database ID: exR0261927 RNA Name: hsa-miR-27b-3p RNA Type: miRNA Chromosome: chr9 Starnd: + Coordinate: Start Site(bp): 95085505 End Site(bp): 95085525 External Links: hsa-miR-27b-3p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand NUAK1 chr12 106063340 106140033 - IDS chrX 149476988 149521096 - AEN chr15 88621337 88632281 + RTL10 chr22 19846138 19854896 - SOX11 chr2 5692384 5701385 + KCNK1 chr1 233614106 233672514 + ALDH3A2 chr17 19648136 19685760 + GIPC1 chr19 14477760 14496149 - LASP1 chr17 38869859 38921770 + LARP4B chr10 806914 931705 - DCTN4 chr5 150708440 150759109 - TMX4 chr20 7977346 8019805 - B4GALT3 chr1 161171310 161177968 - GLTP chr12 109850945 109880541 - PLK2 chr5 58453982 58460139 - URGCP chr7 43875894 43926411 - ONECUT2 chr18 57435374 57491298 + ACER3 chr11 76860867 77026797 + PRKX chrX 3604340 3713649 - LGALS8 chr1 236518000 236552981 + CDR2 chr16 22345936 22437165 - NRBP1 chr2 27427790 27442259 + CANX chr5 179678628 179731641 + IRF4 chr6 391752 411443 + INO80D chr2 205993721 206086303 - PPP1CC chr12 110719680 110742939 - TTYH3 chr7 2631986 2664802 + IGF2BP3 chr7 23310209 23470491 - KPNA6 chr1 32108056 32176563 + STRBP chr9 123109500 123268586 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000384 chr12 27867712 27877119 + hsa_circ_0001247 chr22 46125304 46136418 + hsa_circ_0000942 chr19 46020920 46021352 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010980.2 chr2 222317242 222318653 - AC021092.1 chr19 44103007 44113183 - AC022150.4 chr19 52650437 52653284 - AC093010.3 chr3 114314501 114329714 - AL050341.2 chr1 40256427 40257967 - KCNQ1OT1 chr11 2608328 2699994 - LINC01089 chr12 121795267 121803906 - LINC02381 chr12 54126082 54147485 + NEAT1 chr11 65422774 65445540 + SDCBP2-AS1 chr20 1325405 1378735 + SNHG22 chr18 49814023 49851059 + TUG1 chr22 30969245 30979395 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA