exRNAdisease

Entry Detail

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General Information

Database ID: exR0261977 RNA Name: hsa-miR-30e-5p RNA Type: miRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 40754371 End Site(bp): 40754392 External Links: hsa-miR-30e-5p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CHD1 chr5 98853985 98928957 - TBPL1 chr6 133952170 133990432 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000540 chr14 55799534 55821940 + hsa_circ_0000384 chr12 27867712 27877119 + hsa_circ_0001168 chr20 47691321 47707559 + hsa_circ_0001146 chr20 34241449 34246936 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005034.3 chr2 75697583 75697996 + AC008124.1 chr12 45718046 45727775 - AC012236.1 chr15 31221999 31230838 - AC021078.1 chr5 149494314 149504670 - AL049840.4 chr14 103694516 103695050 - AL137129.1 chr14 61734138 61776260 + DLEU2 chr13 49956670 50125720 - MALAT1 chr11 65497688 65506516 + NEAT1 chr11 65422774 65445540 + NORAD chr20 36045618 36051018 - OIP5-AS1 chr15 41283990 41309737 + SNHG16 chr17 76557764 76565348 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA