Entry Detail



General Information

Database ID:exR0262188
RNA Name:hsa-miR-3648
RNA Type:miRNA
Chromosome:chr21
Starnd:+
Coordinate:
Start Site(bp):8987026End Site(bp):8987046
External Links:hsa-miR-3648



Disease Information

Disease Name:Prostate Cancer
Disease Category:Cancers
MeSH ID:D011471
Type:Neoplasms/Digestive System Neoplasms
Alias:Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate



Expression Detail

GEO ID:GSE134266
Description:Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray)
Experimental Design:Cancer vs Control
Case Disease Type:Prostate Cancer
Case Disease SubType:Bone Metastatic Prostate Cancer
Case Sample:Bone Metastatic Prostate Cancer
Control Sample:Benign Prostatic Hyperplasia
Number of Case:8
Number of Control:9
Number of Samples:17





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MT-CO2
chrMT
7586
8269
+
THAP7
chr22
20999104
21002196
-
CERS4
chr19
8206736
8262421
+
ARL8B
chr3
5122245
5180912
+
EEF1G
chr11
62559596
62574086
-
FNBP4
chr11
47716494
47767443
-
PTGES3
chr12
56663341
56688408
-
AP002990.1
chr11
62559603
62591531
-
PTCH2
chr1
44819844
44843253
-
MAPK9
chr5
180233143
180292099
-
ACTG1
chr17
81509971
81523847
-
ECPAS
chr9
111360692
111484745
-
RNF126
chr19
647526
663233
-
SF3A2
chr19
2236824
2248655
+
TPT1
chr13
45333471
45341370
-
AKIRIN2
chr6
87674860
87702233
-
LZTS3
chr20
3162617
3173592
-
AL133352.1
chr10
100505628
100529881
-
ATP6V0A2
chr12
123712353
123761755
+
SET
chr9
128683424
128696400
+
SH3GLB2
chr9
129007036
129028303
-
PAM16
chr16
4331549
4355607
-
LRRC45
chr17
82023305
82031151
+
SRRM2
chr16
2752626
2772538
+
NDUFB8
chr10
100523740
100530000
-
GAPDH
chr12
6534512
6538374
+
CORO7-PAM16
chr16
4340251
4420494
-
SKI
chr1
2228319
2310213
+
SSR2
chr1
156009048
156020951
-
ARRDC4
chr15
97960703
97973833
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:GSE134266
Sample Source:Blood
Source Fraction:Extracellular Vesicle
Platform:GPL25134
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2519
Sample treatment protocol:The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific).
RNA Extract protocol:Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially.
RNA library preparation protocol:Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA