exRNAdisease

Entry Detail

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General Information

Database ID: exR0262192 RNA Name: hsa-miR-3652 RNA Type: miRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 103930425 End Site(bp): 103930442 External Links: hsa-miR-3652

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ATP5MC3 chr2 175176258 175184607 - GANAB chr11 62624826 62646726 - HDLBP chr2 241227264 241317061 - PGRMC1 chrX 119236245 119244466 + PTMA chr2 231706895 231713541 + RAB15 chr14 64945814 64973226 - AC099811.2 chr17 42119674 42154916 - AP2A1 chr19 49766968 49807113 + AP2M1 chr3 184174689 184184091 + ARHGAP33 chr19 35774532 35788822 + BDNF chr11 27654893 27722058 - BRI3 chr7 98252379 98310441 + CCT6A chr7 56051685 56063989 + FKBP8 chr19 18531751 18544077 - GATC chr12 120446444 120463749 + GDF11 chr12 55743122 55757264 + HLA-DRA chr6 32439878 32445046 + HSP90B1 chr12 103930107 103953645 + MIB2 chr1 1615415 1630610 + RAB5C chr17 42124976 42155044 - SF3A2 chr19 2236824 2248655 + SFPQ chr1 35176378 35193145 - WASF1 chr6 110099819 110180004 - WBP11 chr12 14784582 14803486 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC022819.1 chr15 99157231 99161140 - AL591742.2 chr1 114032393 114034511 + Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA