exRNAdisease

Entry Detail

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General Information

Database ID: exR0262290 RNA Name: hsa-miR-380-3p RNA Type: miRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 101025056 End Site(bp): 101025077 External Links: hsa-miR-380-3p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AGFG1 chr2 227472152 227561214 + KPNA6 chr1 32108056 32176563 + KRAS chr12 25205246 25250936 - MEF2A chr15 99565417 99716466 + ZBTB21 chr21 41986831 42010387 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000712 chr16 68208276 68225678 + hsa_circ_0001723 chr7 91924202 91948826 + hsa_circ_0000711 chr16 68155889 68160513 + hsa_circ_0001740 chr7 117825700 117828459 + hsa_circ_0000744 chr17 15968183 15971435 - hsa_circ_0000552 chr14 71880664 71948928 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand DSCAM-AS1 chr21 40383083 40385358 + FGD5-AS1 chr3 14920347 14948424 - MCM3AP-AS1 chr21 46229196 46259390 + MIR4458HG chr5 8450701 8486930 + OIP5-AS1 chr15 41283990 41309737 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA