exRNAdisease

Entry Detail

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General Information

Database ID: exR0262557 RNA Name: hsa-miR-4508 RNA Type: miRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 23562107 End Site(bp): 23562123 External Links: hsa-miR-4508

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand USP22 chr17 20999596 21043760 - AC005943.1 chr19 1578339 1605445 - ADNP2 chr18 80109262 80147523 + ANAPC1 chr2 111611639 111884690 - ANKRD54 chr22 37830855 37849327 - CDC42BPB chr14 102932380 103057549 - COA1 chr7 43608456 43729717 - CSNK1G2 chr19 1941172 1981338 + CTC1 chr17 8224815 8248056 - EID2 chr19 39538707 39540161 - ESYT2 chr7 158730995 158830253 - FUS chr16 31180110 31194871 + LTBP3 chr11 65538805 65558930 - MBD3 chr19 1573596 1592865 - NDUFB4 chr3 120596328 120602507 + OXTR chr3 8750408 8769628 - PROB1 chr5 139390592 139395104 - SCAF4 chr21 31671000 31732118 - SLBP chr4 1692731 1712344 - TM9SF1 chr14 24189149 24195687 - TMCO3 chr13 113491021 113554590 + UBE3A chr15 25333728 25439051 - URI1 chr19 29923644 30016612 + UROS chr10 125784980 125823258 - USP28 chr11 113797874 113875570 - WRAP53 chr17 7686071 7703502 + ZNF580 chr19 55635016 55643470 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand HCG18 chr6 30286690 30327382 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA