Entry Detail



General Information

Database ID:exR0262717
RNA Name:hsa-miR-4700-3p
RNA Type:miRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):120723233End Site(bp):120723258
External Links:hsa-miR-4700-3p



Disease Information

Disease Name:Prostate Cancer
Disease Category:Cancers
MeSH ID:D011471
Type:Neoplasms/Digestive System Neoplasms
Alias:Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate



Expression Detail

GEO ID:GSE134266
Description:Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray)
Experimental Design:Cancer vs Control
Case Disease Type:Prostate Cancer
Case Disease SubType:Bone Metastatic Prostate Cancer
Case Sample:Bone Metastatic Prostate Cancer
Control Sample:Benign Prostatic Hyperplasia
Number of Case:8
Number of Control:9
Number of Samples:17





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
GAPDH
chr12
6534512
6538374
+
PARP1
chr1
226360691
226408093
-
SEC61A1
chr3
128051641
128071683
+
TTLL12
chr22
43166622
43187134
-
UNC119B
chr12
120710458
120723640
+
CAMTA2
chr17
4967992
4987675
-
FBXO2
chr1
11637018
11655785
-
HADH
chr4
107989714
108035175
+
KDM5B
chr1
202724495
202808487
-
ORMDL1
chr2
189770267
189784364
-
PDIA6
chr2
10783391
10837977
-
RPL34
chr4
108620566
108630412
+
TINAGL1
chr1
31576485
31587686
+
TPT1
chr13
45333471
45341370
-
WDR1
chr4
10074339
10116949
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:GSE134266
Sample Source:Blood
Source Fraction:Extracellular Vesicle
Platform:GPL25134
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2519
Sample treatment protocol:The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific).
RNA Extract protocol:Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially.
RNA library preparation protocol:Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA