exRNAdisease

Entry Detail

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General Information

Database ID: exR0262731 RNA Name: hsa-miR-4709-3p RNA Type: miRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 74480135 End Site(bp): 74480157 External Links: hsa-miR-4709-3p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BCORL1 chrX 129981107 130058083 + COQ8A chr1 226897536 226987545 + DNAJB6 chr7 157335381 157417439 + LAMC1 chr1 183023420 183145592 + PURA chr5 140107777 140125619 + TMEM167A chr5 83052846 83077863 - BIK chr22 43110750 43129712 + CLSTN3 chr12 7129698 7158945 + DHX16 chr6 30653119 30673006 - EMC4 chr15 34225013 34230156 + ETV3 chr1 157121191 157138474 - GATM chr15 45361124 45402327 - MED1 chr17 39404285 39451272 - MED28 chr4 17614641 17634105 + MSH3 chr5 80654652 80876815 + MTRNR2L12 chr3 96617188 96618236 - NDUFA4 chr7 10931943 10940153 - NPC2 chr14 74476192 74494177 - PLBD1 chr12 14503661 14567883 - PLEKHA5 chr12 19129752 19376400 + RACK1 chr5 181236897 181248096 - RBM15B chr3 51391285 51397908 + SLC50A1 chr1 155135344 155138857 + TPRG1L chr1 3625015 3630127 + WNK1 chr12 752579 911452 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA