exRNAdisease

Entry Detail

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General Information

Database ID: exR0262732 RNA Name: hsa-miR-4709-5p RNA Type: miRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 74480175 End Site(bp): 74480196 External Links: hsa-miR-4709-5p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BCORL1 chrX 129981107 130058083 + CBX2 chr17 79778148 79787983 + CTNND1 chr11 57753243 57819546 + DNAJB6 chr7 157335381 157417439 + ERP29 chr12 112013348 112023449 + LAMC1 chr1 183023420 183145592 + ARID4B chr1 235131634 235328219 - CLSTN3 chr12 7129698 7158945 + DHX16 chr6 30653119 30673006 - GFM2 chr5 74721206 74767147 - HNRNPL chr19 38836388 38852347 - HOXB13 chr17 48724763 48729178 - HSP90AA1 chr14 102080738 102139699 - IDH1 chr2 208236227 208266074 - IREB2 chr15 78437431 78501453 + MKKS chr20 10401009 10434222 - MSH3 chr5 80654652 80876815 + NPC2 chr14 74476192 74494177 - PABPC1 chr8 100685816 100722809 - PODXL chr7 131500262 131558217 - PRDX5 chr11 64318121 64321811 + SCAF8 chr6 154733325 154834244 + TIAM2 chr6 154832697 155257723 + UGP2 chr2 63840940 63891562 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005479.1 chr14 74474007 74474864 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA