Entry Detail



General Information

Database ID:exR0262889
RNA Name:hsa-miR-483-3p
RNA Type:miRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):2134142End Site(bp):2134162
External Links:hsa-miR-483-3p



Disease Information

Disease Name:Prostate Cancer
Disease Category:Cancers
MeSH ID:D011471
Type:Neoplasms/Digestive System Neoplasms
Alias:Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate



Expression Detail

GEO ID:GSE134266
Description:Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray)
Experimental Design:Cancer vs Control
Case Disease Type:Prostate Cancer
Case Disease SubType:Bone Metastatic Prostate Cancer
Case Sample:Bone Metastatic Prostate Cancer
Control Sample:Benign Prostatic Hyperplasia
Number of Case:8
Number of Control:9
Number of Samples:17





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ADIPOR2
chr12
1688574
1788674
+
CHP1
chr15
41230839
41281887
+
CLDN11
chr3
170418865
170454733
+
GGA2
chr16
23463542
23521995
-
NF2
chr22
29603556
29698598
+
NFE2L1
chr17
48048329
48061545
+
PARD6B
chr20
50731580
50756795
+
PRRC2B
chr9
131373636
131500197
+
RREB1
chr6
7107597
7251980
+
SYVN1
chr11
65121780
65134533
-
ZNF587
chr19
57849859
57865117
+
KBTBD12
chr3
127915232
127987671
+
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000931
chr19
38226804
38231095
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AL132655.2
chr20
58817132
58817725
-
HCG11
chr6
26521709
26527404
+
MALAT1
chr11
65497688
65506516
+
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
SNHG15
chr7
44983023
44986961
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE134266
Sample Source:Blood
Source Fraction:Extracellular Vesicle
Platform:GPL25134
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2519
Sample treatment protocol:The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific).
RNA Extract protocol:Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially.
RNA library preparation protocol:Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA