exRNAdisease

Entry Detail

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General Information

Database ID: exR0263048 RNA Name: hsa-miR-520h RNA Type: miRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 53742566 End Site(bp): 53742587 External Links: hsa-miR-520h

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ATXN1 chr6 16299112 16761491 - CAMK2N1 chr1 20482391 20486210 - CCDC88C chr14 91271323 91417844 - EEA1 chr12 92770637 92929331 - FYCO1 chr3 45917899 45995824 - GOLGB1 chr3 121663199 121749767 - NAA16 chr13 41311267 41377030 + NEDD4 chr15 55826922 55993746 - OCRL chrX 129539849 129592561 + ZBTB39 chr12 56998836 57006546 - ZNF468 chr19 52838010 52857649 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000467 chr13 21742126 21742538 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC023509.1 chr12 53441741 53467528 + AC024940.6 chr12 31280422 31280895 - ADAMTSL4-AS1 chr1 150560202 150574552 - AL356488.2 chr1 109100193 109100619 + EPB41L4A-AS1 chr5 112160526 112164818 + HCG11 chr6 26521709 26527404 + HOTAIR chr12 53962308 53974956 - KCNQ1OT1 chr11 2608328 2699994 - NEAT1 chr11 65422774 65445540 + NORAD chr20 36045618 36051018 - SNHG20 chr17 77086716 77099902 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA