exRNAdisease

Entry Detail

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General Information

Database ID: exR0263063 RNA Name: hsa-miR-542-3p RNA Type: miRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 134541364 End Site(bp): 134541385 External Links: hsa-miR-542-3p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand EIF2S1 chr14 67360151 67386516 + FOXK1 chr7 4682295 4771442 + LONRF2 chr2 100271875 100322501 - MFN2 chr1 11980181 12013514 + SELENON chr1 25800176 25818221 + SNTB2 chr16 69187129 69309052 + TMEM167A chr5 83052846 83077863 - ZNF100 chr19 21722771 21767579 - ZNF417 chr19 57900296 57916610 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001492 chr5 65284462 65290692 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC074117.1 chr2 27356246 27367622 + AL355075.4 chr14 20343048 20343685 - LINC00665 chr19 36313067 36331770 - NEAT1 chr11 65422774 65445540 + SNHG8 chr4 118278709 118285316 + TUG1 chr22 30969245 30979395 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA