exRNAdisease

Entry Detail

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General Information

Database ID: exR0263234 RNA Name: hsa-miR-574-5p RNA Type: miRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 38868056 End Site(bp): 38868078 External Links: hsa-miR-574-5p

Disease Information

Disease Name: Prostate Cancer Disease Category: Cancers MeSH ID: D011471 Type: Neoplasms/Digestive System Neoplasms Alias: Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

Expression Detail

GEO ID: GSE134266 Description: Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray) Experimental Design: Cancer vs Control Case Disease Type: Prostate Cancer Case Disease SubType: Bone Metastatic Prostate Cancer Case Sample: Bone Metastatic Prostate Cancer Control Sample: Benign Prostatic Hyperplasia Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CCDC88C chr14 91271323 91417844 - CARMIL1 chr6 25279078 25620530 + AHCYL1 chr1 109984765 110023742 + ARID3A chr19 925781 975939 + CHD7 chr8 60678740 60868028 + IDH3A chr15 78131498 78171945 + FAM102A chr9 127940582 127980989 - EEF2K chr16 22206278 22288738 + LRP8 chr1 53242364 53328469 - SMCO4 chr11 93478472 93543391 - ALDOA chr16 30064164 30070457 + ZNF621 chr3 40524878 40574685 + MAP7D1 chr1 36155579 36180849 + RAB10 chr2 26034084 26137454 + TACC1 chr8 38728186 38853028 + KLF11 chr2 10042849 10054836 + TEAD1 chr11 12674421 12944737 + MGRN1 chr16 4616493 4690974 + SLC9A1 chr1 27098809 27166981 - FNDC3A chr13 48975912 49209779 + SLC25A43 chrX 119399336 119454478 + CTSD chr11 1752755 1764573 - PHF20L1 chr8 132775358 132848807 + DCAF8 chr1 160215715 160262549 - PIK3R3 chr1 46040140 46133036 - RHOU chr1 228735479 228746664 + GALNT3 chr2 165747588 165794659 - HOXC8 chr12 54008985 54012769 + NID1 chr1 235975830 236065109 - WSB2 chr12 118032694 118062430 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005394.2 chr19 28435388 28727680 - AC021092.1 chr19 44103007 44113183 - AL358472.3 chr1 153966516 153966930 + DSCAM-AS1 chr21 40383083 40385358 + NEAT1 chr11 65422774 65445540 + SNHG7 chr9 136721366 136728184 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE134266 Sample Source: Blood Source Fraction: Extracellular Vesicle Platform: GPL25134 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2519 Sample treatment protocol: The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific). RNA Extract protocol: Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially. RNA library preparation protocol: Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).

Reference

PMID: NA Title: NA Author: NA Journal: NA Description: NA