Entry Detail



General Information

Database ID:exR0263257
RNA Name:hsa-miR-589-5p
RNA Type:miRNA
Chromosome:chr7
Starnd:-
Coordinate:
Start Site(bp):5495873End Site(bp):5495894
External Links:hsa-miR-589-5p



Disease Information

Disease Name:Prostate Cancer
Disease Category:Cancers
MeSH ID:D011471
Type:Neoplasms/Digestive System Neoplasms
Alias:Prostatic Neoplasms//Prostate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate



Expression Detail

GEO ID:GSE134266
Description:Deep sequencing identified serum extracellular vesicle delivered miR-181a-5p as an indicator for bone-metastatic prostate cancer (microarray)
Experimental Design:Cancer vs Control
Case Disease Type:Prostate Cancer
Case Disease SubType:Bone Metastatic Prostate Cancer
Case Sample:Bone Metastatic Prostate Cancer
Control Sample:Benign Prostatic Hyperplasia
Number of Case:8
Number of Control:9
Number of Samples:17





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007192.1
chr19
18153158
18178117
+
ATP6V0D1
chr16
67438014
67481181
-
FXYD3
chr19
35115879
35124324
+
JPT2
chr16
1678256
1702280
+
MICU1
chr10
72367327
72626191
-
NFIX
chr19
12995608
13098796
+
PACS1
chr11
66070272
66244744
+
PIK3R2
chr19
18153163
18170532
+
RNF169
chr11
74748849
74842413
+
SEC61A1
chr3
128051641
128071683
+
WDR45B
chr17
82614562
82648553
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001134
chr20
21319681
21324846
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC027290.2
chr12
122865335
122867021
+
KCNQ1OT1
chr11
2608328
2699994
-
MALAT1
chr11
65497688
65506516
+
Display:



Experiment Detail

GEO ID:GSE134266
Sample Source:Blood
Source Fraction:Extracellular Vesicle
Platform:GPL25134
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2519
Sample treatment protocol:The blood was centrifuged at 2000 g for 10 min at 4 °C to extract the serum. The serum EV was extracted using Total Exosome Isolation Kit (from serum, Thermo fisher scientific).
RNA Extract protocol:Exosome Purification and RNA Isolation Kit (Norgen Biotek) was employed to purify EV and extract total RNA in EV consequentially.
RNA library preparation protocol:Sample tag and reagents are included in the hybrid need Agilent's micrornas Complete Labeling and Hyb Kit (p/n 5190-0456).



Reference

PMID:NA
Title:NA
Author:NA
Journal:NA
Description:NA