exRNAdisease

Entry Detail

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General Information

Database ID: exR0315577 RNA Name: hsa-miR-1252-5p RNA Type: miRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 79419261 End Site(bp): 79419282 External Links: hsa-miR-1252-5p

Disease Information

Disease Name: Benign Breast Disease Disease Category: Other Diseases MeSH ID: D001941 Type: Diseases Category/Skin and Connective Tissue Diseases Alias: Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease

Expression Detail

GEO ID: GSE73002 Description: A circulating microRNA panel to diagnose breast cancer Experimental Design: Disease vs Control Case Disease Type: Benign Breast Disease Case Disease SubType: NA Case Sample: Benign Breast Disease Control Sample: Non-Cancer Number of Case: 54 Number of Control: 2686 Number of Samples: 2740

Regulatory Relationship

mRNA targets: NA miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001605 chr6 42903447 42905047 + hsa_circ_0001495 chr5 68470703 68471364 + hsa_circ_0001146 chr20 34241449 34246936 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002467.1 chr7 107739999 107744581 - AC005034.3 chr2 75697583 75697996 + AC007952.4 chr17 19112000 19112636 - AC011498.2 chr19 4447304 4448217 + AC067930.1 chr8 143579636 143580670 + AL590617.2 chr6 138692548 138697288 + BX284668.2 chr1 16870945 16883659 + KCNQ1OT1 chr11 2608328 2699994 - LINC01128 chr1 825138 859446 + LINC01278 chrX 63222993 63561095 - LINC01783 chr1 16533886 16536172 - MALAT1 chr11 65497688 65506516 + MIR17HG chr13 91347820 91354579 + NEAT1 chr11 65422774 65445540 + OIP5-AS1 chr15 41283990 41309737 + SNHG15 chr7 44983023 44986961 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE73002 Sample Source: Blood Source Fraction: Serum Platform: GPL18941 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2512 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.). RNA library preparation protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID: 26749252 Title: Novel combination of serum microRNA for detecting breast cancer in the early stage Author: Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T Journal: Cancer Sci. 2016 Mar;107(3):326-34. Description: we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.