Entry Detail


General Information

Database ID:exR0315618
RNA Name:hsa-miR-1277-5p
RNA Type:miRNA
Chromosome:chrX
Starnd:+
Coordinate:
Start Site(bp):118386401End Site(bp):118386424
External Links:hsa-miR-1277-5p



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000417
chr12
69644908
69656342
+
hsa_circ_0001168
chr20
47691321
47707559
+
hsa_circ_0000552
chr14
71880664
71948928
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005034.3
chr2
75697583
75697996
+
AC005082.1
chr7
23205787
23208045
+
AC010327.5
chr19
55216660
55221616
+
AC024940.6
chr12
31280422
31280895
-
AC079781.5
chr7
97851688
97972985
-
AL050341.2
chr1
40256427
40257967
-
DANCR
chr4
52712404
52720351
+
EPB41L4A-AS1
chr5
112160526
112164818
+
HCG11
chr6
26521709
26527404
+
HOTAIR
chr12
53962308
53974956
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
OIP5-AS1
chr15
41283990
41309737
+
PSMA3-AS1
chr14
58265365
58298134
-
SH3BP5-AS1
chr3
15254184
15264515
+
TBC1D3P1-DHX40P1
chr17
59962363
60018975
-
TUG1
chr22
30969245
30979395
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.