exRNAdisease

Entry Detail

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General Information

Database ID: exR0315725 RNA Name: hsa-miR-151a-3p RNA Type: miRNA Chromosome: chr8 Starnd: - Coordinate: Start Site(bp): 140732587 End Site(bp): 140732607 External Links: hsa-miR-151a-3p

Disease Information

Disease Name: Benign Breast Disease Disease Category: Other Diseases MeSH ID: D001941 Type: Diseases Category/Skin and Connective Tissue Diseases Alias: Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease

Expression Detail

GEO ID: GSE73002 Description: A circulating microRNA panel to diagnose breast cancer Experimental Design: Disease vs Control Case Disease Type: Benign Breast Disease Case Disease SubType: NA Case Sample: Benign Breast Disease Control Sample: Non-Cancer Number of Case: 54 Number of Control: 2686 Number of Samples: 2740

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACP1 chr2 264140 278283 + PCDHA1 chr5 140786136 141012347 + PCDHA10 chr5 140855883 141012347 + PCDHA11 chr5 140868183 141012344 + PCDHA12 chr5 140875302 141012347 + PCDHA13 chr5 140882124 141012347 + PCDHA2 chr5 140794852 141012347 + PCDHA3 chr5 140801028 141012347 + PCDHA4 chr5 140806929 141012347 + PCDHA5 chr5 140821604 141012347 + PCDHA6 chr5 140827958 141012347 + PCDHA7 chr5 140834248 141012347 + PCDHA8 chr5 140841187 141012347 + PCDHA9 chr5 140847463 141012344 + PCDHAC1 chr5 140926369 141012344 + PCDHAC2 chr5 140966470 141012347 + STRBP chr9 123109500 123268586 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC044784.1 chr10 8970125 8973468 + AC104794.2 chr2 10083781 10086101 + AL160006.1 chr1 110058340 110062555 + SCARNA9 chr11 93721513 93721865 + TUG1 chr22 30969245 30979395 + Display:

Experiment Detail

GEO ID: GSE73002 Sample Source: Blood Source Fraction: Serum Platform: GPL18941 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2512 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.). RNA library preparation protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID: 26749252 Title: Novel combination of serum microRNA for detecting breast cancer in the early stage Author: Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T Journal: Cancer Sci. 2016 Mar;107(3):326-34. Description: we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.