Entry Detail


General Information

Database ID:exR0315815
RNA Name:hsa-miR-198
RNA Type:miRNA
Chromosome:chr3
Starnd:-
Coordinate:
Start Site(bp):120395703End Site(bp):120395724
External Links:hsa-miR-198



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
C18orf25
chr18
46173553
46266992
+
CGN
chr1
151510510
151538692
+
CS
chr12
56271699
56300391
-
FSTL1
chr3
120392293
120450993
-
UBE2K
chr4
39698109
39782792
+
CCDC103
chr17
44899142
44905390
+
CLTC
chr17
59619689
59696956
+
FAM187A
chr17
44899712
44905390
+
LRRC20
chr10
70298970
70382650
-
MAP1B
chr5
72107234
72209565
+
NECTIN2
chr19
44846175
44889223
+
RRP7A
chr22
42508344
42519796
-
TPGS2
chr18
36777647
36829216
-
TUBA1A
chr12
49184795
49189080
-
ZNF281
chr1
200404940
200410056
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
FTX
chrX
73940435
74293574
-
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.