Entry Detail


General Information

Database ID:exR0315816
RNA Name:hsa-miR-199a-3p
RNA Type:miRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):172144554End Site(bp):172144575
External Links:hsa-miR-199a-3p



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AP3B1
chr5
78000525
78294755
-
DUSP5
chr10
110497907
110511533
+
E2F3
chr6
20401879
20493714
+
EMP1
chr12
13196723
13219941
+
PDXDC1
chr16
14974591
15139339
+
RBM23
chr14
22893204
22919182
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000591
chr15
41961025
41962156
+
hsa_circ_0001731
chr7
100731990
100738448
+
hsa_circ_0000311
chr11
61205096
61205585
+
hsa_circ_0001865
chr9
86292641
86293514
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005082.1
chr7
23205787
23208045
+
AC005165.1
chr7
25593304
25751032
-
AC010542.4
chr16
66549280
66551189
+
AC021078.1
chr5
149494314
149504670
-
AC079781.5
chr7
97851688
97972985
-
AL122035.1
chr14
64422935
64448557
-
AL358472.3
chr1
153966516
153966930
+
MALAT1
chr11
65497688
65506516
+
MIR200CHG
chr12
6963246
6964447
+
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
OIP5-AS1
chr15
41283990
41309737
+
OTUD6B-AS1
chr8
91059318
91070583
-
SCARNA9
chr11
93721513
93721865
+
SNHG1
chr11
62851984
62855953
-
TUG1
chr22
30969245
30979395
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.