Entry Detail


General Information

Database ID:exR0316121
RNA Name:hsa-miR-331-3p
RNA Type:miRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):95308480End Site(bp):95308500
External Links:hsa-miR-331-3p



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ATXN7L3
chr17
44191805
44200113
-
DAG1
chr3
49468703
49535618
+
ITGA5
chr12
54395261
54419266
-
NACC1
chr19
13116862
13141147
+
NDST1
chr5
150485818
150558211
+
RPUSD1
chr16
784974
788397
-
SDC1
chr2
20200797
20225433
-
SRF
chr6
43171269
43181506
+
TRABD
chr22
50185915
50199598
+
VCP
chr9
35056064
35072627
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001866
chr9
86293355
86297981
-
hsa_circ_0001865
chr9
86292641
86293514
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005332.7
chr17
68188547
68189165
+
AC016876.2
chr17
7581964
7584086
-
H19
chr11
1995176
2001470
-
KCNQ1OT1
chr11
2608328
2699994
-
NEAT1
chr11
65422774
65445540
+
PDCD4-AS1
chr10
110869868
110872233
-
SNHG7
chr9
136721366
136728184
-
VPS9D1-AS1
chr16
89711856
89718165
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.