Entry Detail


General Information

Database ID:exR0316154
RNA Name:hsa-miR-3609
RNA Type:miRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):98881700End Site(bp):98881723
External Links:hsa-miR-3609



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
IGF2
chr11
2129112
2141238
-
MAP3K7
chr6
90513573
90587072
-
MYH9
chr22
36281277
36388067
-
PIK3C2A
chr11
17077730
17207983
-
CCNY
chr10
35247025
35572669
+
CCT2
chr12
69585426
69601570
+
GPRIN3
chr4
89236383
89307800
-
ING5
chr2
241687085
241729478
+
NUP98
chr11
3671083
3797792
-
P2RX5-TAX1BP3
chr17
3663063
3696194
-
PBX2
chr6
32184733
32190202
-
RPLP0
chr12
120196699
120201235
-
TAX1BP3
chr17
3662895
3668679
-
WDR74
chr11
62832342
62841809
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL356488.2
chr1
109100193
109100619
+
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.