Entry Detail


General Information

Database ID:exR0316209
RNA Name:hsa-miR-367-3p
RNA Type:miRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):112647877End Site(bp):112647898
External Links:hsa-miR-367-3p



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
FHL1
chrX
136146702
136211359
+
LRP12
chr8
104489231
104589024
-
RALY
chr20
33993646
34108308
+
THOC2
chrX
123600561
123733056
-
ACTB
chr7
5527148
5563784
-
DCP2
chr5
112976702
113022195
+
PKM
chr15
72199029
72231822
-
METTL7A
chr12
50923472
50932510
+
CCNF
chr16
2429394
2458854
+
ATP6V1A
chr3
113747033
113812056
+
SELENOT
chr3
150602875
150630445
+
HSPA4
chr5
133052013
133106449
+
EML4
chr2
42169353
42332548
+
VIM
chr10
17228241
17237593
+
TRIM13
chr13
49995888
50020481
+
MRS2
chr6
24402908
24426194
+
SCML2
chrX
18239313
18354688
-
CGN
chr1
151510510
151538692
+
NCAPD3
chr11
134150119
134225454
-
ADCY9
chr16
3953387
4116442
-
ZNF451
chr6
57086844
57170305
+
SAR1B
chr5
134601149
134649271
-
CALM2
chr2
47160083
47176921
-
CTNNB1
chr3
41194741
41260096
+
NEK4
chr3
52708444
52770946
-
IGSF8
chr1
160091340
160098943
-
SH3PXD2A
chr10
103594027
103855543
-
RAB9A
chrX
13689128
13710504
+
TUBA1C
chr12
49188736
49274603
+
TMED10
chr14
75131469
75176612
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001005
chr2
53921020
53978078
-
hsa_circ_0001414
chr4
56277780
56284152
+
hsa_circ_0000126
chr1
150997086
150999803
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005394.2
chr19
28435388
28727680
-
AC008040.1
chr3
169939353
169966734
-
AC074117.1
chr2
27356246
27367622
+
AC130650.2
chr16
14150833
14153235
+
DAPK1-IT1
chr9
87553454
87554459
+
LINC01128
chr1
825138
859446
+
MALAT1
chr11
65497688
65506516
+
NORAD
chr20
36045618
36051018
-
OIP5-AS1
chr15
41283990
41309737
+
PITPNA-AS1
chr17
1516931
1518096
+
PURPL
chr5
27217714
27496994
+
SNHG5
chr6
85650491
85678932
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.