Entry Detail


General Information

Database ID:exR0316226
RNA Name:hsa-miR-3681-5p
RNA Type:miRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):12199138End Site(bp):12199159
External Links:hsa-miR-3681-5p



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001865
chr9
86292641
86293514
-
hsa_circ_0000652
chr15
90984737
90986710
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006111.2
chr16
3650636
3651703
-
DNAAF4-CCPG1
chr15
55355248
55498360
-
DSCAM-AS1
chr21
40383083
40385358
+
FGD5-AS1
chr3
14920347
14948424
-
MCM3AP-AS1
chr21
46229196
46259390
+
NEAT1
chr11
65422774
65445540
+
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.