Entry Detail


General Information

Database ID:exR0316291
RNA Name:hsa-miR-382-5p
RNA Type:miRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):101054316End Site(bp):101054337
External Links:hsa-miR-382-5p



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
APCDD1
chr18
10454635
10489949
+
BCAS2
chr1
114567557
114581629
-
BCL2L11
chr2
111119378
111168445
+
CAMTA1
chr1
6785454
7769706
+
COBLL1
chr2
164653624
164843679
-
ELK1
chrX
47635521
47650604
-
FOSL1
chr11
65892049
65900573
-
IGF2BP3
chr7
23310209
23470491
-
KMT5A
chr12
123383773
123409353
+
MAPRE2
chr18
34976928
35143470
+
NID1
chr1
235975830
236065109
-
PARM1
chr4
74933095
75050115
+
PDE8A
chr15
84980440
85139145
+
RAB18
chr10
27504174
27542237
+
SCAF11
chr12
45919131
45992120
-
SH3GL1
chr19
4360370
4400547
-
STEAP3
chr2
119223831
119265652
+
STK40
chr1
36339624
36385896
-
TAGLN
chr11
117199370
117207464
+
TUB
chr11
8019244
8106112
+
UBN2
chr7
139230356
139308236
+
WDR4
chr21
42843094
42879568
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC092718.4
chr16
81030770
81031485
+
AC126365.1
chr17
20788071
20789584
+
FGD5-AS1
chr3
14920347
14948424
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
TUG1
chr22
30969245
30979395
+
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.