Entry Detail


General Information

Database ID:exR0316979
RNA Name:hsa-miR-513a-5p
RNA Type:miRNA
Chromosome:chrX
Starnd:-
Coordinate:
Start Site(bp):147213538End Site(bp):147213555
External Links:hsa-miR-513a-5p



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AEN
chr15
88621337
88632281
+
CD276
chr15
73683966
73714514
+
FAM168B
chr2
131047876
131093460
-
GIPC1
chr19
14477760
14496149
-
IGF2BP3
chr7
23310209
23470491
-
ILF3
chr19
10654261
10692417
+
JRK
chr8
142657460
142681968
-
KCTD21
chr11
78171249
78188626
-
KIAA0232
chr4
6781375
6884170
+
MET
chr7
116672196
116798386
+
MTCL1
chr18
8705661
8832778
+
NRBP1
chr2
27427790
27442259
+
PA2G4
chr12
56104537
56113910
+
PAK1
chr11
77321707
77474635
-
PLK2
chr5
58453982
58460139
-
PPP1CC
chr12
110719680
110742939
-
PRLR
chr5
35048756
35230487
-
RHOU
chr1
228735479
228746664
+
SNX27
chr1
151612006
151699091
+
SOX11
chr2
5692384
5701385
+
SS18
chr18
26016253
26091217
-
STRBP
chr9
123109500
123268586
-
TMX4
chr20
7977346
8019805
-
TXN2
chr22
36467046
36481640
-
WASL
chr7
123681943
123749003
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000894
chr19
12825634
12826553
-
hsa_circ_0000540
chr14
55799534
55821940
+
hsa_circ_0001005
chr2
53921020
53978078
-
hsa_circ_0001168
chr20
47691321
47707559
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009133.5
chr16
29808679
29812227
+
AC023509.1
chr12
53441741
53467528
+
AC095055.1
chr4
151139991
151141103
+
AC239868.1
chr1
149861271
149862504
+
CYTOR
chr2
87454781
87636740
+
KCNQ1OT1
chr11
2608328
2699994
-
LINC01578
chr15
92819540
92899701
+
MIR4435-2HG
chr2
111006015
111523376
-
MIR663AHG
chr20
26167817
26251546
-
NEAT1
chr11
65422774
65445540
+
OIP5-AS1
chr15
41283990
41309737
+
SNHG16
chr17
76557764
76565348
+
SNHG20
chr17
77086716
77099902
+
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.