exRNAdisease

Entry Detail

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General Information

Database ID: exR0317326 RNA Name: hsa-miR-624-3p RNA Type: miRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 31014669 End Site(bp): 31014689 External Links: hsa-miR-624-3p

Disease Information

Disease Name: Benign Breast Disease Disease Category: Other Diseases MeSH ID: D001941 Type: Diseases Category/Skin and Connective Tissue Diseases Alias: Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease

Expression Detail

GEO ID: GSE73002 Description: A circulating microRNA panel to diagnose breast cancer Experimental Design: Disease vs Control Case Disease Type: Benign Breast Disease Case Disease SubType: NA Case Sample: Benign Breast Disease Control Sample: Non-Cancer Number of Case: 54 Number of Control: 2686 Number of Samples: 2740

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CBL chr11 119206298 119313926 + GPCPD1 chr20 5544439 5611006 - MDK chr11 46380756 46383837 + PTPA chr9 129110950 129148946 + SOBP chr6 107490106 107661306 + VANGL1 chr1 115641970 115698224 + WSB2 chr12 118032694 118062430 - ZBTB5 chr9 37438102 37465450 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000095 chr1 95609446 95616975 + hsa_circ_0000698 chr16 47531309 47549512 + hsa_circ_0000552 chr14 71880664 71948928 + hsa_circ_0001376 chr3 194169185 194175121 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005034.3 chr2 75697583 75697996 + AC010327.5 chr19 55216660 55221616 + AC016876.2 chr17 7581964 7584086 - AL162171.3 chr14 88589231 88592408 + ARHGAP27P1-BPTFP1-KPNA2P3 chr17 64749663 64781707 - DHRS4-AS1 chr14 23938219 24052555 - MIR17HG chr13 91347820 91354579 + NEAT1 chr11 65422774 65445540 + SNHG1 chr11 62851984 62855953 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE73002 Sample Source: Blood Source Fraction: Serum Platform: GPL18941 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2512 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.). RNA library preparation protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID: 26749252 Title: Novel combination of serum microRNA for detecting breast cancer in the early stage Author: Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T Journal: Cancer Sci. 2016 Mar;107(3):326-34. Description: we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.