Entry Detail


General Information

Database ID:exR0317348
RNA Name:hsa-miR-641
RNA Type:miRNA
Chromosome:chr19
Starnd:-
Coordinate:
Start Site(bp):40282603End Site(bp):40282626
External Links:hsa-miR-641



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AIF1L
chr9
131096476
131123152
+
AKT2
chr19
40230317
40285536
-
C19orf47
chr19
40319536
40348527
-
CDKN1A
chr6
36676460
36687339
+
F11R
chr1
160995211
161021343
-
FOXN3
chr14
89124871
89619149
-
GATAD2B
chr1
153789030
153923360
-
GCNT2
chr6
10492223
10629368
+
GNPTAB
chr12
101745499
101830959
-
HMGA2
chr12
65824131
65966295
+
ICE1
chr5
5420664
5490220
+
JPT1
chr17
75135248
75168281
-
LSM14A
chr19
34172504
34229515
+
MED13L
chr12
115953872
116277719
-
PRSS16
chr6
27247701
27256624
+
SETD7
chr4
139495941
139606699
-
SOCS3
chr17
78356778
78360077
-
SYNJ2BP
chr14
70366499
70417090
-
SYNJ2BP-COX16
chr14
70326064
70417074
-
ZDHHC6
chr10
112424428
112446917
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0001085
chr2
191765289
191789319
+
hsa_circ_0001168
chr20
47691321
47707559
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC125257.1
chr17
41848518
41851447
-
AC239868.1
chr1
149861271
149862504
+
AL034397.3
chrX
66015461
66020422
+
AL049795.2
chr1
32170733
32176568
+
AL355075.4
chr14
20343048
20343685
-
DLEU2
chr13
49956670
50125720
-
LINC00641
chr14
21200079
21206900
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
OIP5-AS1
chr15
41283990
41309737
+
SNHG1
chr11
62851984
62855953
-
SNHG16
chr17
76557764
76565348
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.