Entry Detail


General Information

Database ID:exR0317845
RNA Name:hsa-miR-760
RNA Type:miRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):93846880End Site(bp):93846899
External Links:hsa-miR-760



Disease Information

Disease Name:Benign Breast Disease
Disease Category:Other Diseases
MeSH ID:D001941
Type:Diseases Category/Skin and Connective Tissue Diseases
Alias:Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease



Expression Detail

GEO ID:GSE73002
Description:A circulating microRNA panel to diagnose breast cancer
Experimental Design:Disease vs Control
Case Disease Type:Benign Breast Disease
Case Disease SubType:NA
Case Sample:Benign Breast Disease
Control Sample:Non-Cancer
Number of Case:54
Number of Control:2686
Number of Samples:2740





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABL1
chr9
130713016
130887675
+
ACVR1B
chr12
51951699
51997078
+
ARID3B
chr15
74541177
74598131
+
C6orf89
chr6
36871870
36928964
+
CHTF8
chr16
69118010
69132578
-
DBNDD1
chr16
90004871
90020128
-
DDX54
chr12
113157174
113185479
-
DMWD
chr19
45782947
45792845
-
EFTUD2
chr17
44849948
44899445
-
ITGA5
chr12
54395261
54419266
-
MEF2D
chr1
156463727
156500779
-
PDCD6
chr5
271621
314974
+
PDE8A
chr15
84980440
85139145
+
PDXK
chr21
43719094
43762307
+
RAE1
chr20
57351223
57379211
+
SLC35B2
chr6
44254096
44257890
-
TELO2
chr16
1493344
1510457
+
TSPAN14
chr10
80454166
80533124
+
WSB2
chr12
118032694
118062430
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000458
chr12
124071293
124074996
+
hsa_circ_0000038
chr1
28800065
28802803
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
KCNQ1OT1
chr11
2608328
2699994
-
MALAT1
chr11
65497688
65506516
+
MIR194-2HG
chr11
64889560
64893449
-
NEAT1
chr11
65422774
65445540
+
NORAD
chr20
36045618
36051018
-
SNHG1
chr11
62851984
62855953
-
TUG1
chr22
30969245
30979395
+
Display:



Experiment Detail

GEO ID:GSE73002
Sample Source:Blood
Source Fraction:Serum
Platform:GPL18941
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:2512
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).
RNA library preparation protocol:miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.



Reference

PMID:26749252
Title:Novel combination of serum microRNA for detecting breast cancer in the early stage
Author:Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T
Journal:Cancer Sci. 2016 Mar;107(3):326-34.
Description:we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.