exRNAdisease

Entry Detail

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General Information

Database ID: exR0317860 RNA Name: hsa-miR-7705 RNA Type: miRNA Chromosome: chr8 Starnd: - Coordinate: Start Site(bp): 100703002 End Site(bp): 100703024 External Links: hsa-miR-7705

Disease Information

Disease Name: Benign Breast Disease Disease Category: Other Diseases MeSH ID: D001941 Type: Diseases Category/Skin and Connective Tissue Diseases Alias: Breast Diseases//Breast Disease//Disease, Breast//Diseases, Breast//Endocrine Breast Diseases//Breast Disease, Endocrine//Breast Diseases, Endocrine//Disease, Endocrine Breast//Diseases, Endocrine Breast//Endocrine Breast Disease

Expression Detail

GEO ID: GSE73002 Description: A circulating microRNA panel to diagnose breast cancer Experimental Design: Disease vs Control Case Disease Type: Benign Breast Disease Case Disease SubType: NA Case Sample: Benign Breast Disease Control Sample: Non-Cancer Number of Case: 54 Number of Control: 2686 Number of Samples: 2740

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CTNND1 chr11 57753243 57819546 + FSTL1 chr3 120392293 120450993 - CTNNA1 chr5 138610967 138935034 + EIF3H chr8 116642130 116766925 - MLF1 chr3 158571163 158607252 + NTPCR chr1 232950605 232983882 + PABPC1 chr8 100685816 100722809 - PABPC3 chr13 25095868 25099254 + RPL27 chr17 42998273 43002959 + RPLP2 chr11 809965 812880 + RPP30 chr10 90871716 90908553 + RPS6 chr9 19375715 19380236 - SRSF1 chr17 58000919 58007346 - TTYH2 chr17 74213571 74262020 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: GSE73002 Sample Source: Blood Source Fraction: Serum Platform: GPL18941 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 2512 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.). RNA library preparation protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

Reference

PMID: 26749252 Title: Novel combination of serum microRNA for detecting breast cancer in the early stage Author: Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T Journal: Cancer Sci. 2016 Mar;107(3):326-34. Description: we examined the expression profiles of serum miRNA in several large cohorts to identify novel miRNA that can be used to detect early stage breast cancer.