exRNAdisease

Entry Detail

General Information

Database ID:

exR0351960

RNA Name:

hsa-miR-1181

RNA Type:

miRNA

Chromosome:

chr19

Starnd:

-

Coordinate:

Start Site(bp):

10403505

End Site(bp):

10403525

External Links:

Disease Information

Disease Name:	Polycystic Ovary Syndrome
Disease Category:	Urogenital Diseases and Pregnancy Complications
MeSH ID:	D011085
Type:	Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:	Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID:	GSE86241
Description:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:	Disease vs Control
Case Disease Type:	Polycystic Ovary Syndrome
Case Disease SubType:	NA
Case Sample:	Polycystic Ovary Syndrome
Control Sample:	Control
Number of Case:	8
Number of Control:	9
Number of Samples:	17

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
CDC37	chr19	10391133	10420121	-
CHD7	chr8	60678740	60868028	+
IRS2	chr13	109752695	109786583	-
MAZ	chr16	29806106	29811164	+
PIM1	chr6	37170152	37175428	+
RRP1B	chr21	43659560	43696079	+
ZMIZ1	chr10	79068966	79316528	+
CAMK4	chr5	111223653	111494886	+
ELF1	chr13	40931924	41061440	-
GNAS	chr20	58839718	58911192	+
GSPT1	chr16	11868128	11916082	-
HNRNPA0	chr5	137745651	137754363	-
HNRNPUL2	chr11	62712630	62727457	-
HNRNPUL2-BSCL2	chr11	62690275	62727384	-
IMMT	chr2	86143932	86195770	-
MDFIC	chr7	114922154	115019202	+
PRKAA2	chr1	56645314	56715335	+
RAB21	chr12	71754863	71800286	+
RALY	chr20	33993646	34108308	+
SLC4A4	chr4	71062667	71572087	+
SOX1	chr13	112067149	112071706	+
SPINT2	chr19	38244035	38292615	+
TMEFF1	chr9	100473149	100577636	+
TTC3	chr21	37073226	37203112	+
U2AF1	chr21	43092956	43107587	-
U2AF1L5	chr21	6484623	6499261	-
UBE2D2	chr5	139526431	139628434	+
ZNF282	chr7	149195546	149226238	+

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC007216.1	chr16	11976851	11977850	-

Display:

Experiment Detail

GEO ID:	GSE86241
Sample Source:	Blood
Source Fraction:	Serum
Platform:	GPL21575
Method:	Microarray
Num of detected RNA Type:	1
Num of detected RNAs of this Type:	1951
Sample treatment protocol:	NA
RNA Extract protocol:	Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:	Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID:	27677182
Title:	The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:	Song DK, Sung YA, Lee H
Journal:	PLoS One. 2016 Sep 27;11(9):e0163756.
Description:	The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.