exRNAdisease

Entry Detail

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General Information

Database ID: exR0351976 RNA Name: hsa-miR-1224-5p RNA Type: miRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 184241405 End Site(bp): 184241423 External Links: hsa-miR-1224-5p

Disease Information

Disease Name: Polycystic Ovary Syndrome Disease Category: Urogenital Diseases and Pregnancy Complications MeSH ID: D011085 Type: Diseases Category/Female Urogenital Diseases and Pregnancy Complications Alias: Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary

Expression Detail

GEO ID: GSE86241 Description: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Experimental Design: Disease vs Control Case Disease Type: Polycystic Ovary Syndrome Case Disease SubType: NA Case Sample: Polycystic Ovary Syndrome Control Sample: Control Number of Case: 8 Number of Control: 9 Number of Samples: 17

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ARF3 chr12 48935723 48957487 - DHCR7 chr11 71428193 71452868 - ZNF621 chr3 40524878 40574685 + SEC14L1 chr17 77088749 77217101 + EMC10 chr19 50476400 50490870 + RACGAP1 chr12 49976923 50033136 - THBD chr20 23045633 23049672 - ENSA chr1 150600851 150629612 - SLC9A3R1 chr17 74748628 74769353 + STK4 chr20 44966479 45080021 + LDOC1 chrX 141111605 141177129 - UBL5 chr19 9827892 9830115 + HOXB8 chr17 48611377 48615292 - ANKRD52 chr12 56237807 56258384 - TRAM2 chr6 52497408 52577060 - RNF157 chr17 76142465 76240493 - STC1 chr8 23841929 23854806 - LMBR1 chr7 156668946 156893216 - CALU chr7 128739292 128773400 + ATP6V1A chr3 113747033 113812056 + KIAA1522 chr1 32741830 32774970 + IKBKB chr8 42271302 42332653 + XPO7 chr8 21919662 22006585 + MIER3 chr5 56919602 56971675 - DYRK1B chr19 39825350 39834201 - TBC1D20 chr20 435480 462543 - MAPKAPK2 chr1 206684944 206734283 + OPA3 chr19 45527427 45602212 - AK2 chr1 33007940 33080996 - FYCO1 chr3 45917899 45995824 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009133.5 chr16 29808679 29812227 + AP000766.1 chr11 107312132 107316271 - NEAT1 chr11 65422774 65445540 + TUG1 chr22 30969245 30979395 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: GSE86241 Sample Source: Blood Source Fraction: Serum Platform: GPL21575 Method: Microarray Num of detected RNA Type: 1 Num of detected RNAs of this Type: 1951 Sample treatment protocol: NA RNA Extract protocol: Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea). RNA library preparation protocol: Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.

Reference

PMID: 27677182 Title: The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Author: Song DK, Sung YA, Lee H Journal: PLoS One. 2016 Sep 27;11(9):e0163756. Description: The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.