Entry Detail



General Information

Database ID:exR0351998
RNA Name:hsa-miR-1245b-5p
RNA Type:miRNA
Chromosome:chr2
Starnd:-
Coordinate:
Start Site(bp):188978133End Site(bp):188978153
External Links:hsa-miR-1245b-5p



Disease Information

Disease Name:Polycystic Ovary Syndrome
Disease Category:Urogenital Diseases and Pregnancy Complications
MeSH ID:D011085
Type:Diseases Category/Female Urogenital Diseases and Pregnancy Complications
Alias:Ovary Syndrome, Polycystic//Syndrome, Polycystic Ovary//Stein-Leventhal Syndrome//Stein Leventhal Syndrome//Syndrome, Stein-Leventhal//Sclerocystic Ovarian Degeneration//Ovarian Degeneration, Sclerocystic//Sclerocystic Ovary Syndrome//Polycystic Ovarian Syndrome//Ovarian Syndrome, Polycystic//Polycystic Ovary Syndrome 1//Sclerocystic Ovaries//Ovary, Sclerocystic//Sclerocystic Ovary



Expression Detail

GEO ID:GSE86241
Description:The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Experimental Design:Disease vs Control
Case Disease Type:Polycystic Ovary Syndrome
Case Disease SubType:NA
Case Sample:Polycystic Ovary Syndrome
Control Sample:Control
Number of Case:8
Number of Control:9
Number of Samples:17





Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000118
chr1
117944807
117963271
+
hsa_circ_0000120
chr1
117944807
118009049
+
hsa_circ_0000119
chr1
117944807
117984947
+
hsa_circ_0000116
chr1
117944807
117948267
+
hsa_circ_0000117
chr1
117944807
117957453
+
hsa_circ_0000931
chr19
38226804
38231095
-
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
KCNQ1OT1
chr11
2608328
2699994
-
LINC02228
chr5
25087450
25190956
-
MALAT1
chr11
65497688
65506516
+
NORAD
chr20
36045618
36051018
-
RMRP
chr9
35657751
35658018
-
TUG1
chr22
30969245
30979395
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:GSE86241
Sample Source:Blood
Source Fraction:Serum
Platform:GPL21575
Method:Microarray
Num of detected RNA Type:1
Num of detected RNAs of this Type:1951
Sample treatment protocol:NA
RNA Extract protocol:Total RNA was extracted from 200 ul of serum samples using the Exosomal miRNA Purification kit (Genolution, Seoul, Korea).
RNA library preparation protocol:Desalted Labeled RNA were prepared from 100ng total RNA Agilent's miRNA Complete Labeling and Hyb Kit.



Reference

PMID:27677182
Title:The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome
Author:Song DK, Sung YA, Lee H
Journal:PLoS One. 2016 Sep 27;11(9):e0163756.
Description:The present study was performed to examine the role of the serum miRNA as a biomarker for the diagnosis of PCOS and its relationship with metabolic and reproductive traits.